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Avandia

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Avandia is a brand, drug brand.

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Avandia a.k.a. Rosiglitazone is an antidiabetic drug in the thiazolidinedione class of drugs. It works as an insulin sensitizer, by binding to the PPAR receptors in fat cells and making the cells more responsive to insulin. It is marketed by the pharmaceutical company GlaxoSmithKline as a stand-alone drug or for use in combination with metformin or with glimepiride. First released in 1999, annual sales peaked at approximately $2.5-billion in 2006; however, following a meta-analysis published in the New England Journal of Medicine in 2007 that linked the drug's use to an increased risk of heart attack, sales plummeted to just $9.5-million in 2012. The drug's patent expired in 2012.

  • also known as Rosiglitazone (Avandia), 罗格列酮
  • official website: www.avandia.com

Printed dictionaries and other books with definitions for Avandia

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Google previewThe PDR Pocket Guide to Prescription Drugs (2005)

by Pocket Books

Avandia is a new type of diabetes medication. It can be used alone or in conjunction with insulin, metformin (Glucophage), or a member of the sulfonylurea class of diabetes drugs (Diabinese, Micronase, Orinase). It takes effect slowly. You may not see a reduction in blood sugar levels for the first 2 weeks of therapy, and it may take 2 to 3 months for the medication to deliver maximum results. Most important fact about this drug Always remember that Avandia 160/AVANDAMET.

Google previewThe Nurse's Guide to Teaching Diabetes Self-Management (2006)

by Rita Girouard Mertig, MS, RNC, CNS, DE

Avandia is a first-line drug in the treatment of type 2 diabetes not controlled by diet and exercise. This study suggests that inhaled human insulin is more effective in controlling blood sugar than a first-line drug and could be used early in the treatment of type 2 diabetes (DeFronzo et al., 2005) In another 6-month study, it was reported that Exubera “appears to be effective, well tolerated, and well accepted in patients with type 2 diabetes and provides glycemic control comparable to a ...

Google previewA Roadmap for Curing Cancer, Alzheimer's, and Cardiovascular Disease (2017)

by Paul J. Marangos

Avandia is an oral diabetes drug that effectively controls blood glucose levels in Type II diabetes patients and is a first-in-class drug that increases the effectiveness of insulin in getting glucose into cells, a key problem for diabetics. It was among the first of the insulin sensitizers and offers not only a new and exciting way to treat diabetes, but may also be important in other diseases related to diabetes, such as Alzheimer disease, since the two diseases often appear together. It offers an ...

Google previewEncyclopedia of Forensic and Legal Medicine (2015)

Avandia. On 2 July 2012, the Office of Public Affairs of the United States ...

Google previewThe Encyclopedia of Endocrine Diseases and Disorders (2005)

by William A. Petit, William A. Jr Petit, Christine A. Adamec

Rosiglitazone (Avandia) Pioglitazone (Actos) Acarbose (Precose) Miglitol (Glyset) Metformin (Glucophage) Glyburide/ Micronized Glyburide Glipizide Glimepiride ...

Google previewStedman's Medical Dictionary for the Health Professions and Nursing (2005)

by Thomas Lathrop Stedman

VIOXX AVANDIA.” SEREVENT ADVAIR SENOKOT ZOLOFT RENAGEL VIAGRA ZOCOR BETAPACE ALDAGTONE ZERIT CARAFATE ".

Google previewThe Illustrated Doctors Dictionary (2011)

A medical dictionary written by a doctor for doctors, now illustrated by Joseph C Segen

with the lead article titled AVANDIA: A Perfect Storm performance anxiety Performing anxiety, stage fright A “fightorflight” reaction in an anxious person carrying out an activity in public–e.g., entertaining, public speaking–or in front of others, as in sexual activity, due to fear of poor performance Clinical findings Tachycardia, hypertension, tachypnoea, increased muscle tone. See Anticipatory anxiety, Fightorflight response, Performing arts medicine performance booster A generic term ...

Google previewMosby's Pocket Dictionary of Medicine, Nursing & Health Professions - E-Book (2013)

by Mosby

Avandia, a trademark for an oral antidiabetic (rosiglitazone). avascular /avas'ky.;l. ;r/ [Gk, a, without; L, vasculum, vessel], 1. pertaining to a tissue area that is not receiving a sufficient supply of blood. 2. pertaining to a kind of tissue that does not have blood vessels. avascular graft [Gk, a, without; L, vasculum, vessel; Gk, graphion, stylus], a tissue graft in which there is no infiltration of blood vessels. avascularization [Gk, a, without; L, vasculum, vessel], a diversion of blood flow away from ...

Google previewThe SAGE Encyclopedia of Cancer and Society (2015)

by Graham A. Colditz

In 2012, it pled guilty to criminal charges for promoting Paxil and Wellbutrin for off -label uses, reporting false prices to Medicaid, and failing to report important safety information about Avandia, resulting in a $3 billion settlement, the largest paid by a drug company up to that point. It faced similar class action suits and criminal fines for marketing off-label uses of paroxetine for child patients; has faced charges of bribery in multiple countries, including being found guilty of systematic ...

Google previewEncyclopedia of Sexually Transmitted Diseases (2008)

by Elaine A. Moore, Lisa Marie Moore

Stony Brook reports that a diabetes drug that boosts insulin sensitivity, rosiglitazone (Avandia), might also be helpful to HIV patients with insulin resistance and lipodystrophy. Very small limited trials with eight HIV-positive patients showed an improvement in insulin resistance in many of the patients and benefits to lipodystrophy in that patients showed an increase in peripheral fat and a decrease in visceral fat. See also Lipoatrophy. Gelato, M.C., et al. “Improved Insulin Sensitivity and ...

Google previewEncyclopedia of Obesity (2008)

J - Z by Kathleen Keller

and rosiglitazone maleate [Avandia®]). An alternative nutritional adjunctive therapy, chromium supplementation, may be effective for PCOS women with insulin resistance. Chromium is an essential trace mineral required to maintain insulin health. Low-chromium status is associated with a ...

Google previewConcise Medical Dictionary (2010)

by Elizabeth A. Martin

and rosiglitazone (Avandia), used in the treatment oftype 2 *diabetes mellitus. They act by reducing resistance of the body to its own insulin and may be taken alone or in combination with *metformin or a sulphonylurea. Thiazolidinediones should not be used in patients with heart failure or a history of heart failure. Thiersch's graft see ...

Google previewThe Canadian Encyclopedia of Natural Medicine (2012)

by Sherry Torkos

Drugs like rosiglitazone (Avandia) and pioglitazone (Actos) help insulin work better in the muscle and fat and also reduce glucose production in the liver. 0 The newest class of oral medications, the DPP-4 inhibitors, such as sitagliptin ( Januvia), work by preventing the breakdown of a naturally occurring compound in the body called glucagon-like peptide (GLP-1). GLP-1 reduces blood glucose levels in the body, so by interfering with its breakdown, these drugs allow it to remain active ...

Google previewConcise Dictionary of Biomedicine and Molecular Biology (2001)

by Pei-Show Juo

Avandia A trade name for rosiglitazone maleate used as an oral antidiabetic agent.

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Scrabble value of A1V4A1N1D2I1A1

The value of this 7-letter word is 11 points, but it's not an accepted word in the Official Scrabble Players Dictionary.

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